John Griffiths 

In 1990, John gained a Bachelors degree with honours in Applied Chemistry at Nottingham Trent University by part time study whilst working as an Analytical Chemist for Severn Trent Laboratories. After twelve years in this role, in 1996 he took the decision to leave full-time employment in order to take a Masters Degree at Loughborough University in Analytical Chemistry and Instrumentation which was achieved with Distinction. Following directly on from this he completed a PhD in Ion Mobility / Mass Spectrometry under the supervision of Professor Colin Creaser once again at Nottingham Trent. The subsequent two years were spent working as an Applications Chemist and Technical Trainer at Micromass (Waters), the mass spectrometry manufacturing company. A move into research followed and for the next five years John worked in Cancer Studies at Manchester University in a proteomics-based mass spectrometry role. John now works as Senior Mass Spectrometrist at the Paterson Institute for Cancer Research in Manchester where he is responsible for method development.

John is a Chartered Chemist (CChem) and a member of the Royal Society of Chemistry (MRSC) and is also a long time member of the American society for mass spectrometry (ASMS) and the British mass spectrometry society (BMSS).

 

Selected Recent Publications

    • Navin Chicooree, John R. Griffiths, Yvonne Connolly and Duncan L. Smith Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides. Rapid Commun. Mass Spectrom. (2013). DOI: 10.1002/rcm.6670
    • Navin Chicooree, Yvonne Connolly, Chong-Teik Tan, Angeliki Malliri, Yaoyong Li, Duncan L. Smith and John R. Griffiths, Enhanced detection of ubiquitin isopeptides using reductive methylation, J. Am. Soc. Mass Spectrom., 24, 421, (2013).
    • Navin Chicooree, John R. Griffiths, Yvonne Connolly, Chong-Teik Tan, Angeliki Malliri, Claire Eyers and Duncan L. Smith, A novel approach to the analysis of SUMOylation with the independent use of trypsin and elastase digestion followed by database searching utilising consecutive residue addition to lysine, Rapid Commun. Mass Spectrom., 27, 127, (2013).
    • John R. Griffiths, Simon Perkins, Yvonne Connolly, Lu Zhang, Mark Holland, Valeria Barattini, Luisa Pereira, Anthony Edge, Harald Ritchie and Duncan L. Smith, The utility of porous graphitic carbon as a stationary phase in proteomics workflows: Two-dimensional chromatography of complex peptide samples, J. Chromatogr. A, 1232, 276, (2012).